Medicine and Your DNA

Some genetic variants, or differences in your DNA, cause your body to process a medicine more slowly than the average person. This may mean that you need less of a medicine or that it stays in your body longer. Other variants cause your body to process a medicine faster. That may mean you need a larger dose or that it leaves your body faster.

As a research program, we are always learning and growing. This means the way we offer DNA results may look different in the future. Participants who donated a sample before 2025 may have received a Medicine and Your DNA Report from All of Us. We are no longer offering the Medicine and Your DNA Report to participants while we explore other opportunities to return different types of results to participants.

If a participant told us they wanted a Medicine and Your DNA Report, All of Us checked their DNA for the genes listed below. These genes are known to affect how the body processes medicine. For each gene, All of Us told participants the variant type they have and what that means. We also included a list of medicines that may be affected by their genetics.

It is important to remember that DNA results from All of Us are research results. Before using these results in your care, they will need to be confirmed with a clinical test.

Genetics alone does not determine whether a medicine is appropriate for someone. Weight, health, diet, and other medicines can affect how the body processes medicine.

Always talk to your doctor or health care provider before making any changes to your care. Changing medicines or dosage on your own could be harmful to your health.